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Tuesday, April 21, 2009

Ankylosing Spondylitis of the spine.




This basically means the inflammation and stiffness of a joint and in this selection I picked the spine. This is usually chronic and progressive form of seronegative arthritis. It usually affects the lumbosacral joint. Emedicine explained the Pathophysiology as; " The basic pathologic lesion of ankylosing spondylitis occurs at the entheses, which are sites of attachment to bone of ligaments, tendons, and joint capsules. Enthesopathy results from inflammation, with subsequent calcification and ossification at and around the entheses. Inflammation with cellular infiltration by lymphocytes, plasma cells, and polymorphonuclear leukocytes is associated with erosion and eburnation of the subligamentous bone. The process usually starts at the sacroiliac joints. Other enthesopathic sites include the iliac crest, ischial tuberosity, greater trochanter, patella, and calcaneum. In the paravertebral soft tissues, the lesion manifests as a formation of new bone within the outer layers of the annulus fibrosis of the intervertebral disk. The margins of the disk are invaded by hyperemic granulation tissue arising from the subchondral bone. This tissue replaces the disk fibers with new bone." I quoted the whole thing just in case I missed something and didn't explain it correctly. From what I read, there are no cures for this and it starts at young ages. They usually give pain medication for the pain. This is another one of those "well this sucks" moments. :)

Carotid Dissection

This type of dissection can be spontaneous intracranially or extracranially. It is a significant cause of ischemic strokes which are basically mini strokes. They can be caused by major or minor trauma if there is such a thing. Most ischemic cerebral symptoms arise from thromboembolic events; therefore, early institution of antithrombotic treatment provides the best outcome. its works best if given within three hours. We have beat this horse in interventional so ill just put some cool pictures. Everyone knows that it can be caused during procedure unintentionally. THAT'S NOT A GOOD THING :)

Tuesday, April 7, 2009

THYROID GOITER.....MY GRANNY HAD ONE ONCE


Ok so I picked thyroid goiter, mainly cause its is short and easy to explain and my granny Berry had one removed a while back. I remember when i was little seeing it on her neck and i just thought she was weird and crazy granny had a crazy disease, I was half right. A defect in the normal synthesis of the TSH ( thyroid stimulating hormone) is the most common reason for a goiter in America. It comes form the pituitary (wow imagine that, I probably could of guess that, im really learning :)...) and it enlarges the thyroid. Ok back to my granny, I remember seeing it completely around her neck and then almost on the side after a couple months. She was really scaring looking when she was yelling at me and my bros especially with that huge goiter. Anyways I believe she had hers removed a while ago, but some other treatments are available. One is taking a pill that reduces the TSH. And obviously you can have them surgically removed and i bet now days they dont leave a huge scar. I believe a malignant goiter only happens in like 5%. Also another reason to remove a goiter is cosmetic reasons (I guarantee this is why my granny got hers taken off, she was always complaining about how she looked and well now she doesn't look mean anymore, just a little crazy ;)...) oh yeah you can see enlarged thyroids on xrays.



I LOVE MY GRANNY